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Friends of

Outcomes of our international childhood cancer workshop

Friends of Rosie brought together 40 of the world’s top researchers and clinicians from across the UK, Europe and North America. Together they discussed how better to target treatments for children with cancer.

The international childhood cancer workshop was held in Manchester on the 8th and 9th of June 2022. It came less than two months after MPs listened to impassioned pleas in the House of Commons for a concerted effort to bring together the very best in research, training, and treatment. The aim is to change the approach to childhood cancer once and for all.

Participants brainstormed how to improve the diagnosis and treatment of children’s cancers using state-of-the-art molecular diagnostics. Their goal is to better tailor novel drug treatments to individual children according to the genetic markers present in their tumours. We call this “precision medicine”.

During lively interactive discussions, attendees presented new technical advances in detecting these genetic markers. They focused particularly on how to use a patient’s blood sample, rather than often painful attempts to gather pieces of a tumour.

Collaboration leads to progress

Progress in the diagnosis and subsequent treatment of cancer in children depends strongly on international collaboration between doctors and scientists. Dr Martin McCabe from the Christie Hospital University of Manchester and Professor Bernadette Brennan from The Royal Manchester Children’s Hospital agreed that Friends of Rosie had succeeded in helping children’s cancer doctors to share novel information helping to advance diagnosis and treatment. Through the workshop, they have developed international collaborations to improve the outcomes for children and young people with cancer.

Martin McCabe
Dr Martin McCabe

Dr McCabe said, “By bringing together all of the best precision medicine clinical research in childhood cancer in Europe at present, the Friends of Rosie workshop has demonstrated what the different international platforms have taught us. But, more importantly, the remaining challenges and the populations of children who are still underserved and poorly understood. We have forged new collaborations across the spectrum of childhood cancer and within specific diseases that will lead to new knowledge and much-needed progress.”

Friends of Rosie Trustee and Ewing Sarcoma survivor, Mahesh Vara, said, “It was a real privilege to speak at the Workshop. I appreciated the opportunity to share my experience of childhood cancer with those that attended. I am hopeful for the future. Workshops like this mark another step towards changing the approach to childhood cancer treatment, care and diagnosis. We continue to make a concerted effort to bring together the very best in research, training, and treatment.”

Our thanks go to the pharmaceutical companies – AstraZeneca, Bayer, Novartis and Pfizer – for their generous financial support of the workshop. We will plan another workshop for 2024.

Nancy Dykes

Nancy Dykes

Nancy, 11, was diagnosed with rhabdomyosarcoma when she was just 2 years old. She was treated with Proton Beam Therapy (PBT) in Germany but unfortunately relapsed less than a year later. The family were then sent to Germany for a second round of PBT. Although treatment helped to cure Nancy’s cancer, she has been left with lots of lasting effects which will require ongoing treatment throughout her life. Here Nancy and her mum, Antonia, share their story in the hope it will help others, raise awareness, and raise more money for children’s cancer research.

Prof John Hickman

Prof John Hickman

Why I am a Trustee of CCRF
 
I am a relative of the Larkin family and knew Rosie Larkin ( Friends of Rosie, now CCRF) when she had and then died of neuroblastoma, aged six. At that time, I was a scientist and professor at Manchester University, actively working on the problem of why some cancers do not die despite intensive and toxic therapies.  Seeing Rosie during her unsuccessful therapy and then attending her funeral, besides being emotional, drove me to double down on my own research as well as to support the Charity as best I could as a cancer researcher. I spent over a decade as the Chairman of the Scientific Advisory Board of the CCRF, when the Board moulded policies to ensure that funds raised for research into childhood cancers were distributed only to clinicians and researchers who had the brightest ideas that could impact of cancer medicine for children.
 
My role on the Board
 
As a Trustee,  I hope that my many decades of experience in cancer research and medicine can help the CCRF determine where best the funds that are raised can be invested in cutting edge research and medicine. I am also keen that the CCRF brings together UK and international experts in science and cancer medicine to brainstorm on how best to advance the treatment of childhood cancers.
 
My Background
 
I was a Professor of Pharmacology at Manchester University, working on drug resistance in cancer. I then moved to Paris, where I still live, to head cancer drug discovery at a French pharmaceutical company (Servier). I then headed an EU consortium for six years that brought together researchers from the pharmaceutical industry, universities and biotechnology companies, from all over Europe and the UK, to improve cancer drug discovery. I continue to be active in cancer health policy, publishing in the medical literature.
Katrina

Katrina London

Why I am a Trustee of CCRF

I have spent my professional career representing individuals and families affected by the devastating asbestos-related cancer, mesothelioma, which has no cure and for which there are only a limited number of palliative treatments available on the NHS.

I joined CCRF because I wanted to bring my understanding of the need to raise awareness of less well known cancers and passion for the need to secure improved funding for research to children facing a cancer diagnosis.

My role on the Board

I am responsible for oversight of our collaboration agreements with other charities to co-fund research into cures and treatments for childhood cancers. I also manage our challenge events and help with community fundraising. 

My Background

I am a Senior Associate at Irwin Mitchell LLP and specialise in Asbestos Disease Litigation, acting on behalf of victims of asbestos related diseases and their families.  Over the years, I have undertaken a number of fundraising challenges to raise money for cancer research, including a 1000 mile cycle ride from Glasgow to Southampton.   

Carla

Carla Nuttall

Why I’m a Trustee of CCRF
 
I became a trustee of the Children’s Cancer Research Fund because I believe every child deserves the chance to grow up healthy and with everything to look forward to in life. Like many people, I’ve seen the impact cancer can have on families and I wanted to do something that could make a real difference. This started through my work as an ambassador for Cyclists Fighting Cancer, which supported young people and their families in finding strength, confidence, and joy through movement.
 
That experience shaped my understanding of the challenges families face and the importance of community-led support – but crucially, the clear need for that to go hand-in-hand with targeted research and long-term solutions.
 
This is why I’m so passionate about the work CCRF does and proud to contribute to a cause that gives children and their families, the greatest chance of living a life without limits.
 
My Role on the Board
 
I support CCRF’s mission by bringing my experience in brand, marketing, and communications to the board. My focus is on helping CCRF tell its story in a way that resonates with people – whether that’s families, researchers, donors, or the wider public. I work alongside an incredible team to strengthen CCRF’s voice, build trust, and grow awareness so that more children and families can benefit from the breakthroughs we’re helping to fund.
 
My Background
 
I’m the Executive Director of Corporate Affairs and Marketing for The Growth Company, a social enterprise dedicated to helping people, businesses, and places to thrive through its market-leading insight, employment, skills and business support.
My passion is to help the organisations I work with to communicate with clarity, purpose, and integrity. That’s why I’ve spent my career in strategic communications supporting organisations that want to make a positive difference – CCRF could not fit my sense of purpose any better.